Provided herein are methods treating follicular lymphoma (FL) in subjects having early disease progression after immunochemotherapy using a phosphoinositide-3-kinase (PI3K) inhibitor. In certain embodiments, the methods comprise treating FL in subjects having disease progression within 24 months of initiating first-line or subsequent immunochemotherapy using a phosphoinositide-3-kinase (PI3K) inhibitor.本文提供使用磷酸肌醇-3-激酶(PI3K)抑制劑治療在免疫化學療法之後具有早期疾病演進之個體之濾泡淋巴瘤(FL)的方法。在某些實施例中，該等方法包含在開始第一線或後續免疫化學療法之24個月內使用磷酸肌醇-3-激酶(PI3K)抑制劑治療出現疾病演進之個體中之FL。
