The invention relates to some diaryl macrocyclic compounds, pharmaceutical compositions containing them and methods for using them, including methods for treating cancer, pain, neurological diseases, autoimmune diseases and inflammation.本發明涉及某些二芳基巨環化合物、含有其的醫藥組合物和使用其的方法,包括治療癌症、疼痛、神經疾病、自體免疫疾病和炎症的方法。