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专利权人:
大原薬品工業株式会社
发明人:
三明 達矢
申请号:
JP2015027127
公开号:
JP6238921B2
申请日:
2015.02.16
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
PROBLEM TO BE SOLVED: To provide a tablet containing irbesartan at a high dose, having a high elution speed of irbesartan from the tablet at early stage of production and having no reduction in the elution speed even after the tablet has been preserved under high humidity environment.SOLUTION: There is provided a tablet containing, relative to total weight of the tablet, 40 to 60 wt% of irbesartan, 30 to 50 wt% of dilution agent, 1 to 10 wt% of disintegration agent, 1 to 5 wt% of binding agent and 0.2 to 5 wt% of lubricant, but not anti adhesive agent. The tablet is obtained as follows: the binding agent to powder mixture of the irbesartan, the dilution agent and a part of disintegration agent are added to the binding agent, granules are produced by wet high-speed stirring granulation, and the remaining disintegration agent and lubricant are added to the granules and compressed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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