RIEKER, CLAUS,HUDRY-LABBE, JULIE,SCHMITT, JEROEN ANTONIUS JOHANNES,BOSCHAT, CORINA,SILBER, YVONNE BEATA
申请号：
CA3034187
公开号：
CA3034187A1
申请日:
2017.09.29
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A method of attenuating, treating or preventing cognitive aging in an individual who does not have dementia includes administering to the individual a therapeutically effective amount of a composition containing an omega-3 fatty acid and choline. The method can achieve a benefit that is one or more of decreasing brain atrophy, increasing or maintaining number of synapses, increasing amyloid-ß phagocytosis, or decreasing or maintaining neuroinflammation in the non-demented individual. The method can prevent dementia in an individual at risk thereof, for example an elderly human. The composition can be administered to the individual in a daily dose that provides 5.5 mg/day to 5,500 mg/day of the choline, for example 85 mg/day to 3,500 mg/day of the choline.
