Claus Rieker,Julie Hudry-Labbe,Jeroen Antonius Johannes Schmitt,Corina Boschat,Yvonne Beata Silber
申请号：
US16336294
公开号：
US20200046660A1
申请日:
2017.09.29
申请国别(地区):
US
年份:
2020
代理人:
摘要：
A method of attenuating, treating or preventing cognitive aging in an individual who does not have dementia includes administering to the individual a therapeutically effective amount of a composition containing an omega-3 fatty acid and choline. The method can achieve a benefit that is one or more of decreasing brain atrophy, increasing or maintaining number of synapses, increasing amyloid-β phagocytosis, or decreasing or maintaining neuroinflammation in the non-demented individual. The method can prevent dementia in an individual at risk thereof, for example an elderly human. The composition can be administered to the individual in a daily dose that provides 5.5 mg/day to 5,500 mg/day of the choline, for example 85 mg/day to 3,500 mg/day of the choline.
