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FORMULAÇÃO DE IMUNOGLOBULINAS E MÉTODO DE PREPARAÇÃO DAS MESMAS
专利权人:
BIOGEN MA INC.
发明人:
DAVID J. BURKE,SHAUN E. BUCKLEY,SHERWOOD, RUSS LEHRMAN,BARBARA HORSEY O'CONNOR,JAMES CALLAWAY,CHRISTOPHER PHILLIPS,BARBARA HORSEY OCONNOR
申请号:
PT10005235
公开号:
PT2236154T
申请日:
2004.02.09
申请国别(地区):
PT
年份:
2018
代理人:
摘要:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
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