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Immunoglobulin Formulation and Method of Preparation Thereof
专利权人:
Elan Pharmaceuticals; Inc
发明人:
David J. Burke,Shaun E. Buckley,Sherwood Russ Lehrman,Barhara Horsey O'Connor,James Callaway,Christopher P. Phillips,Barhara Horsey OConnor
申请号:
US13676866
公开号:
US20130071386A1
申请日:
2012.11.14
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
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