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IMMUNOGLOBULIN FORMULATION AND METHOD OF PREPARATION THEREOF
专利权人:
Biogen MA Inc.
发明人:
David J. Burke,Shaun E. Buckley,Sherwood Russ Lehrman,Barbara Horsey O'Connor,James Callaway,Christopher P. Phillips,Barbara Horsey OConnor
申请号:
US15914980
公开号:
US20180194843A1
申请日:
2018.03.07
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.
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