Barbara Horsey O'Connor;Shaun E. Buckley;Sherwood Russ Lehrman;Christopher P. Phillips;James Callaway;David J. Burke
发明人:
David J. Burke,Shaun E. Buckley,Sherwood Russ Lehrman,Barbara Horsey O'Connor,James Callaway,Christopher P. Phillips,Barbara Horsey OConnor
申请号:
US13605590
公开号:
US08900577B2
申请日:
2012.09.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A stable aqueous pharmaceutical formulation comprising a therapeutically effective amount of an antibody, polysorbate 80, a buffer which inhibits polysorbate oxidation is described along with methods of making the preparation. Also described are formulations with high antibody concentrations which maintain fixed volumes and which may be used on patients of variable weight.