Conn, P. Jeffrey,Lindsley, Craig W.,Weaver, Charles David,Stauffer, Shaun R.,Williams, Richard,McDonald, Gregor James,Bartolome-Nebreda, Jose Manuel,Zhou, Ya
申请号：
AU2010295288
公开号：
AU2010295288A1
申请日:
2010.09.21
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
In one aspect, the invention relates to 0-benzyl nicotinamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5)； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions.
