CONN P. JEFFREY,LINDSLEY CRAIG W.,WEAVER CHARLES DAVID,STAUFFER SHAUN R.,WILLIAMS RICHARD,MACDONALD GREGOR JAMES,BARTOLOME-NEBREDA JOSE MANUEL,ZHOU YA
申请号：
IN3322DEN2012
公开号：
IN3322DEN2012A
申请日:
2012.04.17
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
In one aspect, the invention relates to 0-benzyl nicotinamide analogs, derivatives thereof, and related compounds, which are useful as positive allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5)； synthetic methods for making the compounds； pharmaceutical compositions comprising the compounds； and methods of treating neurological and psychiatric disorders associated with glutamate dysfunction using the compounds and compositions.
