ALONSO DE DIEGO SERGIO ALVAR,VAN GOOL MICHIEL LUC MARIA,DELGADO GONZLEZ SCAR,ANDR‰S GIL JOS IGNACIO,TRABANCO SUREZ ANDRS AVELINO
申请号:
IN201727007246
公开号:
IN201727007246A
申请日:
2017.03.01
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention relates to novel 6 7 dihydropyrazolo[1 5 a]pyrazin 4(5H) one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (mGluR2). The invention is also directed to pharmaceutical compositions comprising such compounds to processes for preparing such compounds and compositions and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.