ALONSO DE DIEGO SERGIO ALVAR,VAN GOOL MICHIEL LUC MARIA,MARTA N MARTA N MARA A LUZ,CONDE CEIDE SUSANA,ANDRA S GIL JOSA IGNACIO,DELGADO GONZA LEZ A SCAR,TRESADERN GARY JOHN,TRABANCO SUA REZ ANDRAS AVEL
申请号:
IN201627043665
公开号:
IN201627043665A
申请日:
2016.12.21
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention relates to novel 6 7 dihydropyrazolo 1 5 a pyrazin 4(5H) one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds to processes for preparing such compounds and compositions and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved.