Provided is a further method for detecting neoplasia such as cancer from fluoroscopic images of breasts. A plurality of X-ray images are obtained which include a first X-ray image that is obtained by imaging a breast at a first timing and a second X-ray image that is obtained by imaging the breast at a second timing where blood flow is less than the first timing. An image is generated on the basis of difference in regions that include mammary glands from the first X-ray image and the second X-ray image.
