您的位置: 首页 > 农业专利 > 详情页

Substituted tetrahydropyran spiro pyrrolidinone and piperidinone, preparation and therapeutic use thereof
专利权人:
Zhongli Gao;Ryan Hartung;David Stefany
发明人:
Zhongli Gao,Ryan Hartung,David Stefany
申请号:
US13151925
公开号:
US08217052B2
申请日:
2011.06.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present disclosure relates to a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I):wherein R1, R2, m, n and p are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefore are disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充