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PIPÉRIDINE SPIRO PYRROLIDINONE ET PIPÉRIDINONES SUBSTITUÉS UTILISÉS COMME MODULATEURS DE H3
专利权人:
SANOFI
发明人:
申请号:
EP09793649.6
公开号:
EP2373652B1
申请日:
2009.12.04
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present disclosure relates to a series of substituted N-phenyl-bipyrrolidine carboxamides of formula (I). wherein R1, R2, R3, m, n and p are as described herein. More specifically, the compounds of this invention are modulators of H3 receptors and are, therefore, useful as pharmaceutical agents, especially in the treatment and/or prevention of a variety of diseases modulated by H3 receptors including diseases associated with the central nervous system. Additionally, methods of preparation of substituted N-phenyl-bipyrrolidine carboxamides and intermediates therefor are disclosed.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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