Darren McMurtrie;Paul R. Fatheree;Roland Gendron;Paul Allegretti;Brooke Olson;Robert Murray McKinnell;Seok-Ki Choi;Keith Jendza
发明人:
Paul Allegretti,Seok-Ki Choi,Roland Gendron,Paul R. Fatheree,Keith Jendza,Robert Murray McKinnell,Darren McMurtrie,Brooke Olson
申请号：
US13692538
公开号：
US08569351B2
申请日:
2012.12.03
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention is directed to compounds having the formula:wherein: Ar, X, R3, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds； methods of using such compounds； and process and intermediates for preparing such compounds.
