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Intermediates for preparing dual-acting benzyl triazole antihypertensive agents having angiotensin II type I receptor antagonist activity and neprilysin-inhibition activity
专利权人:
Darren McMurtrie;Paul R. Fatheree;Roland Gendron;Paul Allegretti;Brooke Olson;Robert Murray McKinnell;Seok-Ki Choi;Keith Jendza
发明人:
Paul Allegretti,Seok-Ki Choi,Roland Gendron,Paul R. Fatheree,Keith Jendza,Robert Murray McKinnell,Darren McMurtrie,Brooke Olson
申请号:
US14035042
公开号:
US08895755B2
申请日:
2013.09.24
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention is directed to intermediates for preparing compounds having the formula:wherein: Ar, X, R3 ,and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity.
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