Paul Allegretti,Seok-Ki Choi,Roland Gendron,Paul R. Fatheree,Robert Murray McKinnell
申请号：
US13165975
公开号：
US08227497B2
申请日:
2011.06.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention relates to compounds having the formula:wherein: Q, W, Y, Z, r, and Ar are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds methods of using such compounds and process and intermediates for preparing such compounds.
