Seok-Ki Choi,Paul R. Fatheree,Ryan Hudson,Keith Jendza,Robert Murray McKinnell,Vivek Sasikumar
申请号：
US12826976
公开号：
US08143298B2
申请日:
2010.06.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention is directed to compounds of formula I:wherein Ar, r, R3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds of formula I have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds methods of using such compounds and a process and intermediates for preparing such compounds.
