Paul R. Fatheree;Roland Gendron;Brooke Olson;Robert Murray McKinnell;Seok-Ki Choi
发明人:
Seok-Ki Choi,Roland Gendron,Paul R. Fatheree,Robert Murray McKinnell,Brooke Olson
申请号：
US14151145
公开号：
US20140303222A1
申请日:
2014.01.09
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to compounds having the formula:wherein: Ar, r, R2-3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. These compounds have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds； methods of using such compounds； and process and intermediates for preparing such compounds.
