Jiajia DONG,K. Barry SHARPLESS,Jeffery W. KELLY,Aleksandra BARANCZAK,Wentao CHEN
申请号：
US15316742
公开号：
US20170196985A1
申请日:
2015.06.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
This application describes a compound represented by Formula (I): (I) wherein: Y is a biologically active organic core group comprising one or more of an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group, to which Z is covalently bonded； n is 1, 2, 3, 4 or 5； m is 1 or 2； Z is O, NR, or N； X1 is a covalent bond or —CH2CH2—, X2 is O or NR； and R comprises H or a substituted or unsubstituted group selected from an aryl group, a heteroaryl aryl group, a nonaromatic hydrocarbyl group, and a nonaromatic heterocyclic group. Methods of preparing the compounds, methods of using the compounds, and pharmaceutical compositions comprising the compounds are described as well.
