МУХАММАД Навид (US),БЛЕЙ Кейт Р. (US),ТОБИАС Джеффри (US)
申请号：
RU2010151951/15
公开号：
RU2010151951A
申请日:
2009.05.20
申请国别(地区):
RU
年份:
2012
代理人:
摘要：
1. A compound of formula (II):! ! wherein A is a bond or substituted or unsubstituted amino acid moiety ! B is -H, acetyl, or a substituted or unsubstituted amino acid moiety ! R1 is -H, -CH3, alkilenfosfata moiety, substituted or unsubstituted amino acid moiety or a substituted or unsubstituted nucleoside moiety ! or wherein the group B, taken together with R1, forms a substituted or unsubstituted heterocycloalkyl ! x is 1 or 2 and! m is 0 or 1 where! when A is a bond, x is 1 and R1 is -H, B is a substituted or unsubstituted amino acid moiety and! when A is a bond, x is 2, and R1 is methyl, B is -H or a substituted or unsubstituted amino acid moiety ! or a pharmaceutically acceptable salt or solvate of said compound above. ! 2. A compound according to claim 1, wherein A is a bond, R1 is methyl or -H, and B is a substituted or unsubstituted amino acid moiety. ! 3. A compound according to claim 1, wherein A is a bond. ! 4. A compound according to claim 1, wherein A is a substituted or unsubstituted amino acid moiety. ! 5. A compound according to claim 4, wherein A is an unsubstituted amino acid moiety. ! 6. A compound according to claim 5, wherein A is an unsubstituted glycine moiety. ! 7. A compound according to any one of claims 1-6, wherein B is -H or acetyl. ! 8. A compound according to claim 7, wherein B is acetyl. ! 9. A compound according to claim 7, wherein B is -H. ! 10. A compound according to any one of claims 1-6, wherein B is a substituted or unsubstituted amino acid moiety. ! 11. The compound of claim 10, wherein B is a substituted or unsubstituted glutamate moiety. ! 12. The compound of claim 10 wherein B is an unsubstituted glutamate moiety. ! 13. A compound according to any one of claims 1-6, rD
