BOCK, MARK GARY,MOEBITZ, HENRIK,PANIGRAHI, SUNIL KUMAR,PODDUTOORI, RAMULU,SAMAJDAR, SUSANTA
申请号:
PL14792587
公开号:
PL3033343T3
申请日:
2014.08.14
申请国别(地区):
PL
年份:
2019
代理人:
摘要:
The present invention relates to compounds of formula I: in which n, R1, R2, R3a, R4 and R5 are defined in the Summary of the Invention; capable of inhibiting the activity of MEK. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds and compositions in the management of hyperproliferative diseases like cancer.