נגזרות בנזאמיד לעיכוב פעילותם של 2abl, 1abl ו– 1abl–bcr

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专利权人:

NOVARTIS AG

发明人:

申请号：

IL23556614

公开号：

IL235566A

申请日:

2014.11.06

申请国别(地区):

IL

年份:

2016

代理人:

摘要：

The present invention relates to compounds of formula (I): in which Y, Y1, R1, R2, R3 and R4 are defined in the Summary of the Invention； capable of inhibiting the activity of BCR-ABL1 and mutants thereof. The invention further provides a process for the preparation of compounds of the invention, pharmaceutical preparations comprising such compounds and methods of using such compounds in the treatment of cancers.

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中国工程科技知识中心

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