The present invention discloses a crystal form of an anticancer compound of (R) -3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[3-fluorophenyl -1-dimethylphosphine acyloxy-4-yl] pyridin-2-amine and its preparation method, which have the structural formula showing as formula I. The crystal form of present invention is stable, high purity, no hygroscopicity, high bioavailability and suitable for pharmaceutical preparation.本發明公開了一種抗癌化合物(R)-3-[1-(2,6-二氯-3-氟苯基)乙氧基]-5-[3-氟苯基-1-二甲基膦醯氧-4-基]吡啶-2-胺晶型及其製備方法,其結構式如式I所示。本發明晶型性質穩定,純度高,無吸濕性,生物利用度高,適合藥物製劑需求。
