BERNINGER, MARK,SCARIA, PUTHUPPARAMPIL,WOODLE, MARTIN
申请号：
EP09714125
公开号：
EP2257280A4
申请日:
2009.02.26
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Biomedical nanoparticles are disclosed based on new engineered modular carrier macromolecules, on engineered macromolecules or associated entities providing an internal nanoparticle structure, and compositions for minimizing non-specific binding of the nanoparticles while enabling efficient and convenient targeting to cells and tissues. These nanoparticles may be used to deliver atomic or molecular or associated entities which are useful for diagnostics, primarily in vivo imaging, for therapeutics, for vaccines, or for experimental research. Nanoparticles comprising combinations of active entities such as gene inhibitors with gene expression cassettes or imaging agents with therapeutic agents, and polyamide compounds useful for treatment of microbial infections are also disclosed.
