Haitao Ji,Logan R. Hoggard,Yongqiang Zhang,John A. Wisniewski
申请号:
US15566568
公开号:
US20180092866A1
申请日:
2016.04.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In one aspect, the invention relates to substituted N-([1,1′-biphenyl]-3-yl)-[1,1′-biphenyl]-3-carboxamide analogues, derivatives thereof, and related compound; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders, e.g., various tumors and cancers, associated with β-Catenin/BCL9 protein-protein interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.