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SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS
专利权人:
University of Utah Research Foundation
发明人:
Haitao Ji,Logan R. Hoggard,Yongqiang Zhang,John A. Wisniewski
申请号:
US15566568
公开号:
US20180092866A1
申请日:
2016.04.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
In one aspect, the invention relates to substituted N-([1,1′-biphenyl]-3-yl)-[1,1′-biphenyl]-3-carboxamide analogues, derivatives thereof, and related compound; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders, e.g., various tumors and cancers, associated with β-Catenin/BCL9 protein-protein interaction dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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