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Substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase BTK inhibitors
专利权人:
University of Utah Research Foundation
发明人:
Hariprasad Vankayalapati,Venkataswamy Sorna,Steven L. Warner,David J. Bearss,Sunil Sharma
申请号:
US14433580
公开号:
US09296703B2
申请日:
2013.10.04
申请国别(地区):
US
年份:
2016
代理人:
摘要:
In one aspect, the invention relates to substituted N-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of the BTK kinase; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the BTK kinase. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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