Hariprasad Vankayalapati,Venkataswamy Sorna,Steven L. Warner,Bret Stephens,David J. Bearss,Sunil Sharma
申请号：
US13586603
公开号：
US08987335B2
申请日:
2012.08.15
申请国别(地区):
US
年份:
2015
代理人:
摘要：
In one aspect, the invention relates to substituted (E)-N′-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1 synthetic methods for making the compounds pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
