A pressure measuring device for measuring the internal pressure of the affected part under the fixing member includes a plurality of flexible pressure meters (or called as manometers) and a processor connected to each of the flexible pressure meters. The flexible pressure meters are configured at the inner surface of the fixing member and pasted on the affected part to measure the surface pressure of the affected part, and generate measuring signals according to the measured pressure. The processor is capable of receiving the measuring signals and displaying the surface pressure of the affected part according to the measuring signals, furthermore, by analyzing the measuring signals, the internal pressure corresponded to each of the compartments of the affected part can be found. Accordingly, the pressure measuring device assists to judge if compartment syndrome occurs in the affected part.