HARRISON, BOYD L.,LA, DANIEL,BLANCO-PILLADO, MARIA JESUS,SALITURO, FRANCESCO G.,ROBICHAUD, ALBERT J.
申请号：
ARP180103829
公开号：
AR114044A1
申请日:
2018.12.21
申请国别(地区):
AR
年份:
2020
代理人:
摘要：
1. Formula (1) and its drug acceptable salt compounds, wherein T, r8311；R3，R8313，R8310；74919；R8310；74959；R1 74919，R1°74959，R8309；；74919；R8309；；74955；R8310；7491；R8310；7495；R8311；7491；R8311；7495；R8322；7491；R8322；74955；R8313；7491；R8313；7495；R8309；74919；R8309；74959，R831222 and R1 cubes have values determined in descriptive memory. 1. Including a formula (1) compound and methods of using these compounds, such as a method for treating central nervous system disorders. 1. Property 1: a formula compound (1) or a pharmaceutically acceptable salt, where t is 1 or 2； r831181 is hydrogen or methyl, or at 8315； - 8315； - 8315； - 8315； - 8315； - 8315； - is a double mixture, r831181 is not present； r3s is hydrogen, substituted or unsubstituted tar, substituted or unsubstituted tar, Substituted or unsubstituted bitumen, substituted or unsubstituted carbohydrates,e. Independent hydrogen, halogen, cyanide, hydroxyl, substituted or unsubstituted tar, substituted or unsubstituted heterocycle； r8313 is hydrogen or substituted or unsubstituted tar； r8310； 7491 and r8310； 7495 are independent hydrogen, halogen, cyanogen, hydroxyl, substituted or unsubstituted tar, substituted or unsubstituted Halon； r8313 is hydrogen or substituted or not replaced tar； r8310； 7491 and r8310； 7495 are independent hydrogen, halogen, cyanogen, hydroxyl, substituted or unsubstituted tar, substituted or unsubstituted Halon； O replaced or not replaced asphalt, or r8310；； 7491 and r8310；； 7495 combined to form oxo (= O)；Each R1 74919,R1°74959，R8309；；74919；R8309；；74955；R8310；7491；R8310；7495；R8311；7491；R8311；7495；R8322；7491；R8322；74955；R8313；7491；O r8313； 7495s is hydrogen, halogen, cyanogen, hydroxyl, substituted or unsubstituted tar, substituted or unsubstituted Halon, substituted or unsubstituted heterocycle, or substituted or unsubstituted tar, - ord,-OC（=O）RD1，-NH832222，-N（RD1）832222，O-NRD1（=O）RD1，1. Each RD1 grade is an independent hydrogen, substituted or unsubstituted asphalt, substituted or unsubstituted
