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Antisense formulation
专利权人:
ONCOGENEX TECHNOLOGIES INC.
发明人:
Krilla Nicole D,Nixon Lori,Hayes Thomas K
申请号:
NZ61674509
公开号:
NZ616745A
申请日:
2009.07.13
申请国别(地区):
NZ
年份:
2014
代理人:
摘要:
Disclosed is a liquid formulation comprising: a)an oligonucleotide comprising SEQ ID NO: 1 or comprising a variant oligonucleotide in which no more than 3 non-sequential bases are different from SEQ ID NO: 1 and b)an aqueous carrier comprising an aggregation-preventing compound selected from the group consisting of mono and disaccharides and/or sugar alcohols, wherein the oligonucleotide is present at a concentration of at least 25 mg/ml, and wherein the sequence is as defined in the complete specification.
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