INSTITUTO TECNOLOGICO Y DE ESTUDIOS SUPERIORES DEMONTERREY
发明人:
DARIANA GRACIELA RODRIGUEZ SANCHEZ,CARMEN HERNANDEZ BRENES,GUILLERMO TORRE AMIONE,GERARDO DE JESUS GARCIA RIVAS
申请号：
MX2012014817
公开号：
MX2012014817A
申请日:
2012.12.14
申请国别(地区):
MX
年份:
2014
代理人:
摘要：
Scientific evidence indicates that the compounds present in the fruits of the Annona genus plants have anticarcinogenic, antitumor, antimicrobial and antiparasitic properties as well as hypotensive (decrease in the blood pressure), vasodilator and cardiotonic (tones, balance and strengthens the heart) properties. These last three bioactivities are related to the cardiovascular health, the responsible molecules being unknown, as well as the therapeutic doses. The purpose of the invention is to extract and identify the fractions obtained from the guanabana pulp, guided by the group of mixtures that are focused on the bioactivity level of the fractions in order to detect, measure and evaluate the antiplatelet properties thereof, also reporting the effective doses and possible action mechanisms that mediate this novel effect. This invention is attractive due to the fact that the current drugs used for avoiding the platelet aggregation present more side effects than benefits at short and long terms thus an enriched fraction of a natural source, offers important advantages over the effects of commercial drugs, in addition, said enriched fraction represents a good candidate to be used as active ingredient of food supplements which would offer improvements to patients suffering artery damage caused by blood clots.Se ha documentado evidencia científica que indica que los compuestos presentes en las frutas de plantas del genero Annona tienen propiedades anticancerígenas, antitumorales, antimicrobianas y antiparasitarias así como hipotensivas (reducción de presión arterial), vasodilatadoras y cardiotónica (tonifica, equilibra y fortalece al corazón). Estas tres últimas bioactividades están relacionadas con salud cardiovascular y se desconocen las moléculas responsables, así como las dosis terapéuticas. Es por ello que en la presente invención se persigue el objetivo de extraer e identificar las fracciones obtenidas a partir de pulpa de guanábana, guiados por la agrupación de m
