Gabriel Martinez Botella,Boyd L. Harrison,Albert Jean Robichaud,Francesco G. Salituro,Richard Thomas Beresis
申请号：
US14785171
公开号：
US09512165B2
申请日:
2014.04.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I), and pharmaceutically acceptable salts thereof； wherein, R1, R2, R3a, R3b, R4a, R4b, R5, R6, and R7 are as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.
