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19-NOR C3, 3-DISUBSTITUTED C21-N-PYRAZOLYL STEROIDS AND METHODS OF USE THEREOF
专利权人:
Inc.;Sage Therapeutics
发明人:
Gabriel Martinez Botella,Boyd L. Harrison,Albert Jean Robichaud,Francesco G. Salituro,Richard Thomas Beresis
申请号:
US16428386
公开号:
US20200155576A1
申请日:
2019.05.31
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I):and pharmaceutically acceptable salts thereof; wherein , R1, R2, R3a, R3b, R4a, R4b, R5, R6, and R7 are as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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