BOTELLA, GABRIEL MARTINEZ,HARRISON, BOYD L.,ROBICHAUD, ALBERT JEAN,SALITURO, FRANCESCO G.,BERESIS, RICHARD THOMAS
申请号：
CA2909545
公开号：
CA2909545A1
申请日:
2014.04.17
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Provided herein are 19-nor C3,3-disubstituted C21-pyrazolyl steroids of Formula (I), and pharmaceutically acceptable salts thereof； wherein-, R1, R2, R3a, R3b, R4a, R4b, R5, R6, and R7are as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.
