BOTELLA, Gabriel Martinez,HARRISON, Boyd L.,ROBICHAUD, Albert Jean,SALITURO, Francesco G.,BERESIS, Richard Thomas
申请号：
AU2019279910
公开号：
AU2019279910A1
申请日:
2019.12.09
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2019279910A120200116.pdf#####ABSTRACT Provided herein are 19-nor C3,3-disubstituted steroids of Formula (I): A (R 4)" a Me R2 H H R1 HO H R3 and pharmaceutically acceptable salts thereof； wherein R', R2, R3, and R4 are as defined herein, and A is a heteroaryl ring system comprising 3 or 4 nitrogens as defined herein. Such compounds are contemplated useful for the prevention and treatment of a variety of CNSrelated conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, convulsive disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, and tinnitus.
