MÜLLER, Klaus-Helmut,SCHWARZ, Hans-Georg,ILG, Kerstin,VOERSTE, Arnd,MALSAM, Olga,PORTZ, Daniela,JESCHKE, Peter
申请号:
ES14744504
公开号:
ES2649478T3
申请日:
2014.07.21
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
A compound of formula ** Formula ** in which A is N or C-R1; Z is O or S; each R1 is independently H, halogen, cyano, nitro, OR4, NR5R6, C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C (X) R7, C (O) OR8, C ( O) NR11R12, S (O) mR9, S (O) 2NR11R12, N (R10) C (O) R7, N (R10) C (O) NR11R12, N (R10) S (O) 2R9 or N (R10) S (O) 2NR11R12; or C3-C7 cycloalkyl, C4-C8 cycloalkylalkyl, C6-C14 cycloalkyl or C5-C7 cycloalkenyl, each optionally substituted with 1 to 4 substituents independently selected from the group consisting of halogen, cyano, nitro, C1-C4 alkyl, C1 haloalkyl -C4, OR4a and S (O) mR9a; or C1-C6 alkyl substituted with 1 to 4 substituents independently selected from the group consisting of cyano, OR4, NR5 R6, C (X) R7, S (O) mR9 and S (O) 2NR11R12; R2 is H, halogen, cyano, S (O) mR9 or S (O) 2NR11R12; or C3-C6 cycloalkyl, optionally substituted with 1 to 4 substituents independently selected from the group consisting of halogen, cyano, C1-C4 alkyl and C1-C4 haloalkyl; or C1-C4 alkyl substituted with 1 to 2 substituents independently selected from the group consisting of cyano, OR4 and S (O) mR9; R3 is H, C1-C4 alkyl, C2-C3 alkenyl, C (X) R7 or C (O) OR8; or C1-C2 alkyl substituted with OR4; or C1-C2 alkyl substituted with phenyl; Q is phenyl or a 5- or 6-membered heteroaromatic ring system, each optionally substituted with 1 to 5 substituents independently selected from the group consisting of halogen, cyano, nitro, Si (R15) 3, OR4, NR5R6, C1- alkyl C6, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C2-C6 alkynyl, C2-C6 haloalkynyl, C (X) R7, C (O) OR8, C (X) NR11R12, S (O) mR9 , S (O) 2NR11R12, OC (O) R7, OC (O) OR8, OC (O) NR11R12, OS (O) 2R9, OS (O) 2NR11R12, N (R10) C (O) R7, N (R10 ) C (O) NR11R12, N (R10) S (O) 2R9, N (R10) S (O) 2NR11R12 and R14; each R4 is independently H, C1-C4 alkyl or C1-C4 haloalkyl; or C3-C7 cycloalkyl or C4-C8 cycloalkylalkyl, each optionally substituted with 1 to 4 substituents independently selected from the