Paolo Lazzari;Gabriele Murineddu;Gerard Aime Pinna;Stefania Ruiu
发明人:
Paolo Lazzari,Stefania Ruiu,Gerard Aime Pinna,Gabriele Murineddu
申请号：
US12645415
公开号：
US08227620B2
申请日:
2009.12.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Pyrazole derivatives of the following formula (I), having affinity for the cannabinoidergic CB1 and/or CB2 receptors:wherein:R is a group selected from C1-C10 alkyl；aryl, arylalkyl or arylalkenyl, not substituted or having from one to four substituents, equal to or different from each other；A is a group selected from the following: an ether group of formula —(CH2)—O—(CH2)v—R″ wherein v is equal to 1 or 2；R″ is as defined in the present application；a ketone group of formula —C(O)—Z′, wherein Z′ is as defined in the present application；a substituent having an hydroxyl function of formula —CH(OH)—Z′, being as defined in the present application；an amide substituent of formula —C(O)—NH-T′, T′ being as defined in the present application；B is a group as defined in the present application；D is an heteroaryl optionally substituted.
