The invention relates to small molecules having biological and therapeutic activity. Particularly, the invention relates to small molecules having lipolytic and anti-adipogenic activity. Two examples of such molecules are 4-methyl-2-(octanoylamino) pentanoic acid and N-isopentyloctanamide. The invention further relates to methods of preventing or treating skin conditions such as cellulite using small molecules having lipolytic and anti- adipogenic activity.本發明係關於具有生物及治療活性之小分子。特定言之,本發明係關於具有解脂及抗成脂活性之小分子。此等分子之兩實例係4-甲基-2-(辛醯基胺基)戊酸及N-異戊基辛醯胺。本發明進一步關於利用具有解脂及抗成脂活性之小分子預防或治療諸如脂肪團(cellulite)之皮膚病之方法。