MACDONALD, LYNN L,MURPHY, ANDREW, J. AJ,MCWHIRTER, JOHN J,TU, NAXIN N,VORONINA, VERA V,GURER, CAGAN C,MEAGHER, KAROLINA K,STEVENS, SEAN S,.麥克唐納,.莫菲,.麥克沃克,.圖,.沃羅寧那,.古雷爾,.梅格爾,.史蒂文斯
申请号:
HK14111660.0
公开号:
HK1198171A
申请日:
2014.11.19
申请国别(地区):
HK
年份:
2015
代理人:
摘要:
The invention provides a genetically modified non-human animal that comprises in its genome unarranged T cell receptor gene loci, as well as non-human embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.