METHODS OF TREATING A NEURODEGENERATIVE DISEASE农业专利-农业学术服务平台

发明人:: FRIEDHOFF, LAWRENCE,凡德赫夫劳伦斯,凡德赫夫勞倫斯,LEWIS, BRYAN,路易斯布莱恩,路易斯布萊恩,PISCITELLI, STEPHEN,皮希泰利史蒂芬,皮希泰利史蒂芬,KISHNANI, KUNAL,基许纳尼库诺,基許納尼庫諾,RAMASWAMY, SHANKAR,拉马斯瓦密珊卡,拉馬斯瓦密珊卡

摘要：: The present application relates to new uses of 5-HT6 receptor antagonists, specifically high doses of 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline, and to the combination of 5-HT6 receptor antagonists, specifically 3-phenylsulfonyl-8-piperazinyl-1yl-quinoline, with, an acetylcholinesterase inhibitor for the treatment of a neurodegenerative disease.本申請案係有關一種5-HT6受體拮抗劑(明確言之,高劑量之3-苯基磺醯基-8-哌基-1-基-喹啉)之新穎用途,及有關一種5-HT6受體拮抗劑(明確言之,3-苯基磺醯基-8-哌基-1-基-喹啉)與乙醯膽鹼酯酶抑制劑之組合,其係用於治療神經退化性疾病。