DEVAUX, BRIGITTE,HONGO, JO-ANNE S.,PRESTA, LEONARD G.,SHELTON, DAVID L.
申请号:
CA2412494
公开号:
CA2412494C
申请日:
2001.06.22
申请国别(地区):
CA
年份:
2012
代理人:
摘要:
The invention concerns agonist anti-trkC monoclonal antoibodies which mimiccertain biological activities of NT-3, the native ligand of trkC. Theinvention further concerns the use of such antibodies in the prevention and/ortreatment of cellular degeneration, including nerve cell damage associatedwith acute nervous cell system injury and chronic neurodegenerative diseases,including peripheral neuropathy.