JANSEN, TIMOTHY,ZERHUSEN, JAIME,KUANG, JIN-QIANG,TOM, SAMSON,YOO, DANA
申请号：
ARP110100509
公开号：
AR080222A1
申请日:
2011.02.18
申请国别(地区):
AR
年份:
2012
代理人:
摘要：
Placental Fluid Product comprising Therapeutic cells of placenta and placental dispersion comprising placental factors. The cells of placenta and placental dispersion derived from placental tissue. A placental Tissue can optionally be a Chorion, amnion, Chorion Trophoblasts or without.The placental product of the present Invention is useful for treating a patient with a lesion tissue (For example a wound or burn) by applying the product on the placental injury. Claim 1: a Therapeutic product, characterized in that it comprises: placental cells in placenta at least approximately 10.000 per ml of placental product； and placental factors that include one or more Extracellular Matrix Proteins, one or more protease inhibitor, one or more of one or more growth factors, angiogenic factors, and one or more MMPs.Claim 2: The therapeutic product of claim 1, wherein the one or more Extracellular Matrix Proteins Fibronectin, one or more protease inhibitors timp is a, the one or more Growth Factors is a TGF - and bFGF is one or more angiogenic factors.Claim 3: Therapeutic product of claim 2, wherein the placenta cells are in a quantity of less than approximately 1000000 per ml of Product placental Fibronectin, is a concentration of at least 740 ng / m Product and placental I We approximately 361.000 ng / ml of the product is placental, timp-1 timp-1 concentration in a total of at least 6.5 pg / ml and placental Product less than approximately 15000 ng / ml TGF is tgfr1 placental product, at a concentration of at least 250 pg / ml and placental Product less. Approximately 26.000 pgfml placental product, bFGF is a concentration of at least 900 pg / ml and placental Product less than approximately 47000 pg / ml of the product is placental, and mmp-9 in a concentration of at least 13000 total MMP pg / ml and placental Product less. Approximately 1000 ng / ml of placental product.Claim 1: a Therapeutic product, characterized in that it comprises: placental cells in placenta
