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ВАКЦИНЫ STREPTOCOCCUS PNEUMONIAE
专利权人:
УАЙТ ЭлЭлСи (US)
发明人:
ХАНДКЕ Лакшми (US),РАШИДБАИГИ Аббас (US)
申请号:
RU2012151376/10
公开号:
RU2012151376A
申请日:
2011.05.25
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. The polyvalent immunogenic composition comprising a plurality of capsular polysaccharides from Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F, conjugated to a carrier protein, and also comprising 2 -fenoksietanol (2-PE) .2. The polyvalent immunogenic composition according to claim 1, characterized in that said composition comprises seven or more capsular polysaccharides from Streptococcus pneumoniae serotypes 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F and 23F. 3. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that said composition comprises 2-PE at a concentration of 7 mg / ml to 15 mg / ml.4. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that said composition comprises 2-PE at a concentration of about 10 mg / ml.5. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that said composition comprises not less than 7 mg / mL of 2-RE.6. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that said composition comprises not less than 10 mg / ml of 2-RE.7. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that said composition comprises not less than 15 mg / ml of 2-RE.8. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that the aforementioned composition also includes an adjuvant and the aforementioned adjuvant is alyuminiya.9 phosphate. The polyvalent immunogenic composition according to any one of claims 1-2, characterized in that the antigenicity of an immunogenic composition remains stable for at least 1 year, 1.5 years, 2 years, or 2.5 goda.10. The polyvalent immunogenic composition1. Поливалентная иммуногенная композиция, включающая множество капсульных полисахаридов из серотипов Streptococcus pneumoniae 1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F и 23F, конъюгиров
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