ZHANG, XIAOJUN,YANG, WU,TRIPATHY, SASMITA,RUEL, REJEAN,RICHTER, JEREMY,JIANG, WEN,HALPERN, OZ SCOTT,GILLARD, JAMES R.,RUEDIGER, EDWARD H.,REZNIK, SAMUEL KAYE,PRIESTLEY, ELDON SCOTT
申请号：
ARP170101789
公开号：
AR108906A1
申请日:
2017.06.28
申请国别(地区):
AR
年份:
2018
代理人:
摘要：
Include any compounds of this kind. These compounds are skewed analgesics.Or the B-arrest warrant of the No.2 angiopathy receiver dyingThey can be used as medicines. 1. Requirement 1: A compound characterized by formula (1).Or a saltOr a stereoisomerA dwarfDiabetic isomersTaurus,A drug-acceptable salt or solution.Among them: Ring A is the remainder of a formula (2) or (3)；W is N or CR18310；W',In each caseChoose to be independent of N.This is itS,And CR8310A,At least one W'is not CR8310Y.At most,If you have registered, please login first.The selection of R1 and R2 is independent of H.C832183318832626 - Tar,C832183318832626 - Halogenated tar,C83218331；C.C8321C83331；Another wayR1 and R2,Together with the atoms they connect to1. Polymerization to form C8323833183267 cyclo or four to six heterosexual atoms.The substitutes for cyclopropyl or non-cyclopropyl are 0-4F and 0-1OH.R8310,In each caseSelection is independent of H.F,LL,Uh...I,CN,OhN (R749192)；C8321883318C83323 - Tar,C832183318C83323-halide,C8321C83331；C83218331；C8321C83331；C83238331；R7491,In each caseSelection is independent of H.C832183318C8324 - Asphalt,C832183318C8324-Halide,E.C832183318C8324-hydroxielquilo and C83838331832626-cyclo；Or two R74919,Plus the nitrogen atoms they bind to.Together, they form a different cycle of five to six members, including 0-2 additional heteromorphic atoms selected from N.This is it.This is 5-tetrazolilo.SO83238H,PO8322JH,PO83238H83222,Coor,Or other members of the formula group (4)；R,In each caseSelection is independent of H.C832183318832626 - Tar,C832183318832626 - Halogenated tar,C83218331；C8332383331；C. C83268331832183208 ARIL-C832188331268 AKILO；Heterotropic Cycle-C832183-83331-832626-Asphalt,Among them, the heteromorphic period is a group of 4-10 members, with 1-3 heteromorphic atoms selected from N.Or, orWhere Aries and heterosexuality are replaced,EverybodyA. There are 0-3 selected C83218331832323 rental groups；Halo.H O C83218331-fluorescence；R738,In each caseSelection is
