PURPOSE: A manufacturing method of gum containing pilocarpine is provided to use a simple mixing process.CONSTITUTION: A manufacturing method of gum containing pilocarpine comprises the following: a step of laminating 5.0 weight% of cellulose powder, mounting 18.0 weight% of a gum base on the laminated cellulose powder layer, and increasing temperature thereof to 80-140°C for 2-5 minutes a step of injecting 26.5 weight% of D-sorbitol, 1.0 weight% of silicon dioxide, 1.0 weight% of L-menthol, 2.0 weight% of starch, 0.5 weight% of triacetin, 15.0 weight% of white sugar, 0.8 weight% of mint, 1.0 weight% of an emulsifier, 0.5 weight% of natural sweetener into a mixer and primarily mixing at 25-70°C and 3-10 rpm for 5-10 minutes a step of injecting the warm gum base into the first mixture and secondarily mixing the same a step of mixing 26.5 weight% of D-sorbitol into the second mixture and conducting a third mixing at 25-70°C and 3-10 rpm for 2-5 minutes a step of primarily pulverizing the third mixture at a temperature of 20°C or less, a humidity of 40% or less, and a rate of 3 mesh a step of manufacturing gum powder by secondarily pulverizing the first pulverized product to 1.0 pie or less a step of drying the gum powder at room temperature for 36 hours or more a step of mixing 0.2 weight% of pilocarpine and 2.0 weight% of stearic acid magnesium into 97.8 weight% of the gum powder and a step of molding the mixture.COPYRIGHT KIPO 2013[Reference numerals] (AA) Heating a gum base (BB) Inject D-sorbitol, silicon dioxide, L-menthol, starch, triacetin, white sugar, mint, and an emulsifier and firstly combine at the temperature of 25-70°C and 30-10 RPM for 5-10 minutes (CC) Mix/secondly combine the gum base (DD) Mix, thirdly combine D-sorbitol (EE) Firstly pulverize, Secondly pulverize (FF) Dry (GG) Mold필로카르핀 함유 껌 제조방법 및 이에 의하여 제조된 필로카르핀 함유 껌이 제공된다. 본 발명의 일 실시예에 따른 필로카르핀 함유 껌 제조방법은 트레이 상에 5.0 중량%의 셀룰로오즈 분말을 적층하고, 적층된 셀롤로오즈 분말층 상에 18.0 중량%의 껌베이스를 적재하고, 80-140℃의