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Peptide having inhibition of osteoclast activation and differentiation and use thereof
专利权人:
Caregen Co.; Ltd.
发明人:
CHUNG, Yong Ji,KIM, Eun Mi,LEE, Eung Ji,HAN, A Reum,KWON, Hyun Jung
申请号:
ES14898754
公开号:
ES2770631T3
申请日:
2014.08.05
申请国别(地区):
ES
年份:
2020
代理人:
摘要:
A peptide which is formed from an amino acid sequence selected from the group comprising amino acid sequences of SEQ ID NO: 1 to SEQ ID NO: 3, according to the present invention, has osteoclast differentiation and activation inhibition and is highly effective for preventing or treating bone diseases related to the destruction of the bone. A peptide, according to the present invention, reduces expression of cathepsin K and TRAP related to osteoclast differentiation, inhibits nuclear translocation of NF-kB, and ultimately inhibits osteoclast differentiation. Provided is a composition, for preventing or treating bone diseases, comprising the peptide.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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