MARTIN KEITH,WRAITH DAVID,JANSSON LOTTA,JAHRAUS ANDREA,VROLIX KATHLEEN
申请号:
IN201717021375
公开号:
IN201717021375A
申请日:
2017.06.19
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention provides a composition which comprises the following Thyroid Stimulating Hormone Receptor (TSHR) peptides: (i) all or part of the amino acid sequence KKKKYVSIDVTLQQLESHKKK (SEQ ID NO: 1) or a part thereof or a sequence having at least 60% sequence identity to SEQ ID NO:1; and (ii) all or part of the amino acid sequence GLKMFPDLTKVYSTD (SEQ ID NO: 2) or a part thereof or a sequence having at least 60% sequence identity to SEQ ID NO:2. The present invention also relates to the use of such a composition for the prevention or suppression of activating autoantibody formation in Graves disease.